Inferring disease architecture and predictive ability with
LDpred2-auto.
F Privé, C Albiñana, B Pasaniuc, BJ Vilhjálmsson.
https://doi.org/10.1101/2022.10.10.511629
Publicly Available Privacy-preserving Benchmarks for
Polygenic Prediction.
MJ Witteveen, EM Pedersen, J Meijsen, MR Andersen, F Privé, D Speed,
and BJ Vilhjálmsson.
https://doi.org/10.1101/2022.10.10.510645
Identifying and correcting for misspecifications in GWAS
summary statistics and polygenic scores.
F Privé, J Arbel, H Aschard, BJ Vilhjálmsson.
https://doi.org/10.1016/j.xhgg.2022.100136
Accounting for age of onset and family history improves power
in genome-wide association studies.
EM Pedersen, E Agerbo, O Plana-Ripoll, J Grove, JW Dreier, KL
Musliner, M Bækvad-Hansen, G Athanasiadis, A Schork, D Demontis, J
Bybjerg-Grauholm, DM Hougaard, T Werge, M Nordentoft, O Mors, S
Dalsgaard, J Christensen, AD Børglum, PB Mortensen, JJ McGrath, F Privé,
BJ Vilhjálmsson.
https://doi.org/10.1016/j.ajhg.2022.01.009
Harnessing the power of population cohorts to study the
relationship between endocrine-metabolic disorders and
depression.
A Jespersen, Z Yilmaz, BJ Vilhjálmsson.
in press
Interplay of ADHD Polygenic Liability With Birth-Related,
Somatic, and Psychosocial Factors in ADHD: A Nationwide
Study.
I Brikell, T Wimberley, C Albinana, BJ Vilhjálmsson, E Agerbo, AD
Borglum, D Demontis, AJ Schork, S LaBianca, T Werge, DM Hougaard, M
Nordentoft, O Mors, PB Mortensen, LV Petersen, S Dalsgaard.
https://doi.org/10.1176/appi.ajp.21111105
Multi-PGS enhances polygenic prediction: weighting 937
polygenic scores.
C Albiñana, Z Zhu, AJ Schork, A Ingason, H Aschard, I Brikell, CM
Bulik, LV Petersen, E Agerbo, J Grove, M Nordentoft, DM Hougaard, T
Werge, AD Børglum, PB Mortensen, JJ McGrath, BM Neale, F Privé, BJ
Vilhjálmsson.
https://doi.org/10.1101/2022.09.14.22279940
ADuLT: An efficient and robust time-to-event
GWAS.
EM Pedersen, E Agerbo, O Plana-Ripoll, J Steinbach, MD Krebs, DM
Hougaard, T Werge, M Nordentoft, A Børglum, KL Musliner, A Ganna, AJ
Schork, PB Mortensen, JJ McGrath, F Privé, BJ Vilhjálmsson.
https://doi.org/10.1101/2022.08.11.22278618
Deep integrative models for large-scale human
genomics.
AI Sigurdsson, D Westergaard, O Winther, O Lund, S Brunak, BJ
Vilhjálmsson, S Rasmussen.
https://doi.org/10.1101/2021.06.11.447883
Identification of 64 new risk loci for major depression,
refinement of the genetic architecture and risk prediction of recurrence
and comorbidities.
TD Als, M Kurki, J Grove, G Voloudakis, K Therrien, J Naamanka, TT
Nielsen, K Veerapen, D Levey, J Bendl, J Bybjerg-Grauholm, B Zheng, D
Demontis, A Rosengren, G Athanasiadis, M Bækved-Hansen, P Qvist, B
Walters, H Stefánsson, K Musliner, V Manikandan, L Farajzadeh, J
Thirstrup, S Dinesen, BJ Vilhjálmsson, JJ McGrath, M Mattheisen, S
Meier, iPSYCH-Broad Consortium, E Agerbo, K Stefánsson, M Nordentoft, T
Werge, DM Hougaard, PB Mortensen, M Stein, J Gelernter, I Hovatta, P
Roussos, MJ Daly, O Mors, A Palotie, and AD Børglum.
https://doi.org/10.1101/2022.08.24.22279149
Polygenic scoring accuracy varies across the genetic ancestry
continuum in all human populations.
Y Ding, K Hou, Z Xu, A Pimplaskar, E Petter, K Boulier, F Privé, BJ
Vilhjálmsson, LO Loohuis, B Pasaniuc.
https://doi.org/10.1101/2022.09.28.509988
Genetic correlates of vitamin D-binding protein and 25
hydroxyvitamin D in neonatal dried blood spots.
C Albiñana, Z Zhu, N Borbye-Lorenzen, S Grundvad Boelt, AS Cohen, K
Skogstrand, NR Wray, JA Revez, F Privé, LV Petersen, C Bulik, O
Plana-Ripoll, KL Musliner, E Agerbo, A Børglum, DM Hougaard, M
Nordentoft, T Werge, PB Mortensen, BJ Vilhjálmsson, JJ
McGrath.
https://doi.org/10.1101/2022.06.08.22276164
Discriminating bipolar disorder type I and II using polygenic
risk scores for bipolar disorder, schizophrenia and major
depression.
J-CPG Debost, E Agerbo, BJ Vilhjálmsson, PB Mortensen, T Munk-Olsen,
LV Petersen.
in press
Polygenic risk and episode polarity among individuals with
bipolar disorder.
S Hasseris, C Albiñana, BJ Vilhjálmsson, PB Mortensen, SD
Østergaard, KL Musliner.
in press
Genetic liability to posttraumatic stress disorder and its
association with postpartum depression.
KB Madsen, X Liu, C Albiñana, BJ Vilhjálmsson, PB Mortensen, DM
Hougaard, M Nordentoft, T Werge, O Mors, AD Børglum, T
Munk-Olsen.
in press
Portability of 245 polygenic scores when derived and applied
in the same cohort.
F Privé, H Aschard, S Carmi, L Folkersen, C Hoggart, P O’Reilly, BJ
Vilhjálmsson.
https://doi.org/10.1016/j.ajhg.2021.11.008
Large uncertainty in individual PRS estimation impacts
PRS-based risk stratification.
Y Ding, K Hou, K Burch, S Lapinska, F Privé, BJ Vilhjálmsson, S
Sankararaman, B Pasaniuc.
https://doi.org/10.1101/2020.11.30.403188
Correcting for contamination with bovine serum
albumin-associated vitamin D metabolites in protein extracts from
neonatal dried blood spots.
SG Boelt, O Plana-Ripoll, C Albiñana, BJ Vilhjálmsson, JJ McGrath,
AS Cohen.
https://doi.org/10.1186/s13104-022-06077-1
Early life injuries and the development of attention-deficit
hyperactivity disorder.
T Wimberley, I Brikell, EM Pedersen, E Agerbo, BJ Vilhjálmsson, C
Albiñana, F Privé, A Thapar, K Langley, L Riglin, M Simonsen, HS
Nielsen, AD Børglum, M Nordentoft, PB Mortensen, S Dalsgaard.
https://doi.org/10.4088/JCP.21m14033
Genome-wide association study of febrile seizures identifies
seven new loci implicating fever response and neuronal excitability
genes.
L Skotte, J Fadista, J Bybjerg-Grauholm, V Appadurai, MS Hildebrand,
TF Hansen, K Banasik, J Grove, CA Climent, F Geller, CF Bjurström, BJ
Vilhjálmsson, M Coleman, JA Damiano, R Burgess, IE Scheffer, OBV
Pedersen, C Erikstrup, D Westergaard, KR Nielsen, E Sørensen, MT Bruun,
X Liu, H Hjalgrim, TH Pers, PB Mortensen, O Mors, M Nordentoft, JW
Dreier, A Børglum, J Christensen, DM Hougaard, A Buil, A Hviid, M
Melbye, H Ullum, SF Berkovic, T Werge, B Feenstra.
https://doi.org/10.1093/brain/awab260
Using the UK Biobank as a global reference of worldwide
populations: application to measuring ancestry diversity from GWAS
summary statistics.
F Privé
https://doi.org/10.1093/bioinformatics/btac348
Pervasive Downward Bias in Estimates of Liability-Scale
Heritability in Genome-wide Association Study Meta-analysis: A Simple
Solution.
A D Grotzinger, J de la Fuente, F Privé, M G. Nivard, E M
Tucker-Drob
https://doi.org/10.1016/j.biopsych.2022.05.029
Optimal linkage disequilibrium splitting.
F Privé
https://doi.org/10.1093/bioinformatics/btab519
Investigating the shared genetic architecture between
multiple sclerosis and inflammatory bowel diseases.
Y Yang, H Musco, S Simpson-Yap, Z Zhu, Y Wang, X Lin, J Zhang, B
Taylor, J Gratten, Y Zhou
https://doi.org/10.1038/s41467-021-25768
Finding hidden treasures in summary statistics from
genome-wide association studies.
F Privé, Z Zhu, BJ Vilhjálmsson.
https://doi.org/10.1038/s41588-021-00824-z
Improved genetic prediction of complex traits from
individual-level data or summary statistics.
Q Zhang, F Privé, BJ Vilhjálmsson, D Speed.
https://doi.org/10.1038/s41467-021-24485-y
Estimating the effective sample size in association studies
of quantitative traits.
A. Ziyatdinov, J Kim, D Prokopenko, F Privé, F Laporte, P Loh, P
Kraft, H Aschard
https://doi.org/10.1093/g3journal/jkab057
Leveraging both individual-level genetic data and GWAS
summary statistics increases polygenic prediction.
C Albiñana, J Grove, JJ McGrath, E Agerbo, NR Wray, CM Bulik, M
Nordentoft, DM Hougaard, T Werge, AD Børglum, PB Mortensen, F Privé, BJ
Vilhjálmsson
https://doi.org/10.1016/j.ajhg.2021.04.014
Evaluating the interrelations between individual genetic
liability and psychiatric family history in risk for autism.
D Schendel, TM Laursen, C Albiñana, BJ Vilhjalmsson, C Ladd-Acosta,
MD Fallin, K Benke, B Lee, J Grove, A Kalkbrenner, L Ejlskov, D
Hougaard, J Bybjerg-Grauholm, M Bækvad-Hansen, AD Børglum, T Werge, M
Nordentoft, PB Mortensen, E Agerbo.
https://doi.org/10.1002/aur.2629
Multitrait GWAS to connect disease variants and biological
mechanisms.
H Julienne, V Laville, ZR McCaw, Z He, V Guillemot, C Lasry, A
Ziyatdinov, C Nerin, A Vaysse, P Lechat, H Ménager, W Le Goff, M-P Dube,
P Kraft, I Ionita-Laza, BJ Vilhjálmsson, H Aschard.
https://doi.org/10.1371/journal.pgen.1009713
Anorexia nervosa and inflammatory bowel diseases - diagnostic
and genetic associations.
JT Larsen, Z Yilmaz, BJ Vilhjálmsson, LM Thornton, ME Benros, KL
Musliner, T Werge, DM Hougaard, PB Mortensen, CM Bulik, LV
Petersen.
https://doi.org/10.1002/jcv2.12036
Genetic, Clinical, and Sociodemographic Factors Associated
With Stimulant Treatment Outcomes in ADHD.
I Brikell, T Wimberley, C Albiñana, EM Pedersen, BJ Vilhjálmsson, E
Agerbo, D Demontis, AD Børglum, A Schork, S LaBianca, T Werge, M
Nordentoft, O Mors, D Hougaard, A Thapar, PB Mortensen, S
Dalsgaard.
https://doi.org/10.1176/appi.ajp.2020.20121686
Developmental exposure to vitamin D deficiency and subsequent
risk of schizophrenia.
C Albiñana, SG Boelt, AS Cohen, Z Zhu, KL Musliner, BJ Vilhjálmsson,
JJ McGrath.
https://doi.org/10.1016/j.schres.2021.06.004
A polygenic risk score improves risk stratification of
obstructive coronary artery disease beyond clinical risk factors in
patients with stable chest symptoms.
MK Christiansen, S Winther, L Nissen, BJ Vilhjálmsson, L Frost, JK
Johansen, PL Møller, SE Schmidt, J Westra, NR Holm, HK Jensen, EH
Christiansen, DF Guðbjartsson, H Hólm, K Stefánsson, HE Bøtker, M
Bøttcher, M Nyegaard.
https://doi.org/10.1161/CIRCGEN.120.003298
Polygenic Liability and Recurrence of Depression in Patients
With First-Onset Depression Treated in Hospital-Based
Settings.
KL Musliner, KK Andersen, E Agerbo, C Albiñana, BJ Vilhjálmsson, VM
Rajagopal, J Bybjerg-Grauholm, M Bækved-Hansen, CB Pedersen, MG
Pedersen, T Munk-Olsen, ME Benros, T Als, J Grove, T Werge, AD Børglum,
DM Hougaard, O Mors, M Nordentoft, PB Mortensen, NP Suppli.
https://doi.org/10.1001/jamapsychiatry.2021.0701
Polygenic liability, stressful life events and risk for
developing severe depression in early life: A nationwide register-based
case-cohort study.
KL Musliner, E Agerbo, BJ Vilhjálmsson, C Albiñana, TD Als, SD
Østergaard, PB Mortensen.
https://doi.org/10.1017/s0033291721001410
Risk of Major Depression, Polygenic Risk Score for
Depression, Parental Socio-Economic Status and History of Mental
Disorders: A Danish Population-Based Study.
E Agerbo, BB Trabjerg, AD Børglum, AJ Schork, BJ Vilhjálmsson, CB
Pedersen, C Hakulinen, C Albiñana, DM Hougaard, J Grove, JJ McGrath, J
Bybjerg-Grauholm, O Mors, O Plana-Ripoll, T Werge, NR Wray, PB
Mortensen, KL Musliner.
https://doi.org/10.1001/jamapsychiatry.2020.4172
LDpred2 : better, faster, stronger.
F Privé, J Arbel, BJ Vilhjálmsson.
https://doi.org/10.1093/bioinformatics/btaa1029
Polygenic risk score, psychosocial environment and the risk
of attention-deficit/hyperactivity disorder.
SD Østergaard, BB Trabjerg, TD Als, C Albiñana Climent, F Privé, BJ
Vilhjálmsson, M Bækvad-Hansen, J Bybjerg-Grauholm, DM Hougaard, M
Nordentoft, T Werge, D Demontis, PB Mortensen, AD Børglum, O Mors, E
Agerbo.
https://doi.org/10.1038/s41398-020-01019-6
Efficient toolkit implementing best practices for principal
component analysis of population genetic data.
F Privé, K Luu, MG Blum, JJ McGrath, BJ Vilhjálmsson.
https://doi.org/10.1093/bioinformatics/btaa520
Performing highly efficient genome scans for local adaptation
with R package pcadapt version 4.
F Privé, K Luu, BJ Vilhjálmsson, MGB Blum.
https://doi.org/10.1093/molbev/msaa053
Polygenic Risk Score, Psychosocial Environment and the Risk
of ADHD.
https://doi.org/10.1038/s41398-020-01019-6
Families, health-registers, and biobanks – making the
unmeasurable measurable.
C Albiñana, BJ Vilhjálmsson, JJ McGrath.
https://doi.org/10.1016/j.biopsych.2020.06.025
Nature and prevalence of combinations of mental disorders and
their association with excess mortality in a population-based cohort
study.
O Plana-Ripoll, KL Musliner, S Dalsgaard, NC Momen, N Weye, MK
Christensen, E Agerbo, KM Iburg, TM Laursen, PB Mortensen, CB Pedersen,
LV Petersen, DF Santomauro, BJ Vilhjálmsson, HA Whiteford, JJ
McGrath.
https://doi.org/10.1002/wps.20802
Genetic liability to major depression and risk of childhood
asthma.
X Liu, T Munk-Olsen, C Albiñana, BJ Vilhjálmsson, E Pedersen, V
Schlünssen, M Bækvad-Hansen, J Bybjerg-Grauholm, M Nordentoft, A
Børglum, T Werge, D Hougaard, PB Mortensen, E Agerbo.
https://doi.org/10.1016/j.bbi.2020.07.030
Linking the association between circRNAs and Alzheimer’s
disease progression by multi-tissue circular RNA characterization.
I-J Lo, J Hill, BJ Vilhjálmsson, J Kjems.
https://doi.org/10.1080/15476286.2020.1783487
Polygenic risk and progression to bipolar or psychotic
disorders among individuals diagnosed with unipolar depression.
K Musliner, M Krebs, C Albiñana Climent, BJ Vilhjálmsson, E Agerbo,
P Zandi, D Hougaard, M Nordentoft, A Børglum, T Werge, PB Mortensen, S
Østergaard.
https://doi.org/10.1176/appi.ajp.2020.19111195
Association Between Childhood Green Space, Genetic Liability,
and the Incidence of Schizophrenia.
K Engemann, J-C Svenning, E Agerbo, L Arge, A Børglum, A Dupont, C
Erikstrup, O Hertel, D Hougaard, JJ McGrath, PB Mortensen, M Nordentoft,
CE Sabel, T Sigsgaard, C Tsirogiannis, BJ Vilhjálmsson, T Werge, CB
Pedersen, HT Horsdal.
https://doi.org/10.1093/schbul/sbaa058
Association between Mental Disorders and Subsequent Medical
Conditions.
NC Momen, O Plana-Ripoll, E Agerbo, ME Benros, A Børglum, MK
Christensen, S Dalsgaard, L Degenhardt, P de Jonge, J-C Debost, M
Fenger-Grøn, JM Gunn, KM Iburg, LV Kessing, RC Kessler, TM Laursen, C
Lim, O Mors, PB Mortensen, K Musliner, M Nordentoft, CB Pedersen, LV
Petersen, AR Ribe, AM Roest, S Saha, AJ Schork, KM Scott, HJ Sørensen,
TJ Stedman, M Vestergaard, BJ Vilhjálmsson, T Werge, N Weye, HA
Whiteford, A Prior, JJ McGrath.
https://doi.org/10.1056/nejmoa1915784
Symbiosis genes show a unique pattern of introgression and
selection within a Rhizobium leguminosarum species
complex.
MI Cavassim Alves, S Moeskjær, C Moslemi, B Fields, A Bachmann, BJ
Vilhjálmsson, MH Schierup, JPW Young, SU Andersen.
https://doi.org/10.1099/mgen.0.000351
JASS: Command Line and Web interface for the joint analysis
of GWAS results.
H Julienne, P Lechat, V Guillemot, C Lasry, C Yao, R Araud, V
Laville, BJ Vilhjálmsson, H Menager, H Aschard.
https://doi.org/10.1093/nargab/lqaa003
Extreme genetic signatures of local adaptation during Lotus
japonicus colonization of Japan.
N Shah, T Wakabayashi, Y Kawamura, C Skovbjerg, M-Z Wang, Y
Mustamin, Y Isomura, V Gupta, H Jin, T Mun, N Sandal, F Azuma, E Fukai,
Ü Seren, S Kusakabe, Y Kikuchi, S Nitanda, T Kumaki, M Hashiguchi, H
Tanaka, A Hayashi, M Sønderkær, K Nielsen, K Schneeberger, BJ
Vilhjálmsson, R Akashi, J Stougaard, S Sato, M Schierup, SU
Andersen.
https://doi.org/10.1038/s41467-019-14213-y
Headaches and polygenic scores.
BJ Vilhjálmsson, F Privé.
https://ng.neurology.org/content/5/6/e368
Making the Most of Clumping and Thresholding for Polygenic
Scores.
F Privé, BJ Vilhjálmsson, H Aschard, MG Blum.
https://doi.org/10.1016/j.ajhg.2019.11.001
Association of Childhood Exposure to Nitrogen Dioxide and
Polygenic Risk Score for Schizophrenia With the Risk of Developing
Schizophrenia.
HT Horsdal, E Agerbo, JJ McGrath, BJ Vilhjálmsson, S Antonsen, AM
Closter, A Timmermann, J Grove, P Mok, RT Webb, CE Sabel, O Hertel, T
Sigsgaard, C Erikstrup, DM Hougaard, T Werge, M Nordentoft, A Børglum, O
Mors, PB Mortensen, J Brandt, C Geels and CB Pedersen.
https://doi.org/10.1001/jamanetworkopen.2019.14401
Association Mapping and Disease: Evolutionary Perspectives.
S Besenbacher, T Mailund, BJ Vilhjálmsson, MH Schierup.
https://doi.org/10.1007/978-1-4939-9074-0_17
Transgenerational effects of inter-ploidy cross direction on
reproduction and seed development in Arabidopsis thaliana F1 hybrid
triploids.
D Duszynska, BJ Vilhjálmsson, R Castillo Bravo, S Swamidatta, TE
Younger, MTA Donoghue A Comte; M Nordborg, TF Sharbel, G Brychkova, PC
McKeown; C Spillane.
https://doi.org/10.1007/s00497-019-00369-6
The nature of nurture: Effects of parental genotypes.
A Kong, G Thorleifsson, ML Frigg, BJ Vilhjálmsson, AI Young, TE
Thorgeirsson, S Benonisdottir, A Oddsson, BV Halldorsson, G Masson, D
Gudbjartsson, A Helgason, G Bjornsdottir, U Thorsteinsdottir, K
Stefansson.
https://doi.org/10.1126/science.aan6877
PhenoSpD: an atlas of phenotypic correlations and a multiple
testing correction for the human phenome.
J Zheng, T Richardson, L Millard, G Hemani, C Raistrick, BJ
Vilhjálmsson, P Haycock, T Gaunt.
https://doi.org/10.1093/gigascience/giy090
Covariate selection for association screening in
multi-phenotype genetic studies.
H Aschard, V Guillemot, BJ Vilhjálmsson, CJ Patel, D Skurnik, J Yu,
B Wolpin, P Kraft, N Zaitlen.
https://doi.org/10.1038/ng.3975
Nationwide Genomic Study in Denmark Reveals Remarkable
Population Homogeneity.
G Athanasiadis, J Cheng, BJ Vilhjálmsson, FG Jørgensen, TD Als, S Le
Hellard, T Espeseth, PF Sullivan, CM Hultman, PC Kjærgaard, MH Schierup,
and T Mailund.
https://doi.org/10.1534/genetics.116.189241
Response to Day et al.
H Aschard, BJ Vilhjálmsson, A Joshi, AL Price, P Kraft.
https://doi.org/10.1016/j.ajhg.2015.12.020
Modeling linkage disequilibrium increases accuracy of
polygenic risk scores.
BJ Vilhjálmsson, J Yang, H Finucane, A Gusev, S Lindström, S Ripke,
G Genovese, P-R Loh, G Bhatia, R Do, M Pato, C Pato, T Hayeck, H-H Won,
Schizophrenia Working Group of the PGC, the Discovery, Biology, and Risk
of Inherited Variants in Breast Cancer (DRIVE) study, S Kathiresan, M
Pato, C Pato, R Tamimi, E Stahl, N Zaitlen, B Pasaniuc, MH Schierup, P
De Jager, N Patsopoulos, S McCarroll, M Daly, S Purcell, D Chasman, B
Neale, M Goddard, P Visscher, P Kraft, N Patterson, AL Price.
https://doi.org/10.1016/j.ajhg.2015.09.001
Adjusting for heritable covariates can bias effect estimates
in genome-wide association studies.
H Aschard, BJ Vilhjálmsson, A Joshi, AL Price, P Kraft.
https://doi.org/10.1016%2Fj.ajhg.2014.12.021
Polygenic Risk Score, Parental Socioeconomic Status, Family
History of Psychiatric Disorders and the Risk of Schizophrenia: A Danish
Population-Based Study.
E Agerbo, PF Sullivan, BJ Vilhjálmsson, CB Pedersen, O Mors, AD
Børglum, DM Hougaard, MV Hollegaard, S Meier, S Ripke, NR Wray, PB
Mortensen.
https://doi.org/10.1001/jamapsychiatry.2015.0346
DNA methylation variation in Arabidopsis has a genetic basis
and shows evidence of local adaptation.
MJ Dubin, P Zhang, D Meng, M-S Remigereau, EJ Osborne, FP Casale, P
Drewe, A Kahles, BJ Vilhjálmsson, J Jagoda, S Irez, V Voronin, Q Song, Q
Long, G Rätsch, O Stegle, RM Clark, M Nordborg.
https://doi.org/10.7554/eLife.05255
Mixed model with correction for case-control ascertainment
increases association power.
T Hayeck, NA Zaitlen, P-R Loh, BJ Vilhjálmsson, S Pollack, A Gusev,
J Yang, G-B Chen, ME Goddard, PM Visscher, N Patterson, AL
Price.
https://doi.org/10.1016/j.ajhg.2015.03.004
Efficient Bayesian mixed model analysis increases association
power in large cohorts.
P-R Loh, G Tucker, BK Bulik-Sullivan, BJ Vilhjálmsson, HK Finucane,
RM Salem, DI Chasman, PM Ridker, BM Neale, B Berger, N Patterson, AL
Price.
http://dx.doi.org/10.1101/007799
Maximizing the Power in Genome-wide Association Studies of
Principal Components from Correlated Phenotypes.
H Aschard, BJ Vilhjálmsson, N Greliche, P-E Morange, D-A Trégouët, P
Kraft.
https://doi.org/10.1016/j.ajhg.2014.03.016
Leveraging population admixture to characterize the
heritability of complex traits.
N Zaitlen, B Pasaniuc, S Sankararam, G Bhatia, J Zhang, A Gusev, T
Young, A Tandon, S Pollack, BJ Vilhjálmsson, TL Assimes, SI Berndt, WJ
Blot, S Chanock, N Franceschini, PG Goodman, J He, AJM Hennis, A Hsing,
SA Ingles, W Isaacs, RA Kittles, EA Klein, LA Lange, B Nemesure, N
Patterson, D Reich, BA Rybicki, JL Stanford, VL Stevens, SS Strom, EA
Whitsel, JS Witte, J Xu, C Haiman, JG Wilson, C Kooperberg, D Stram, AP
Reiner, H Tang, AL Price.
https://doi.org/10.1038/ng.3139
Partitioning Heritability of Regulatory and
Cell-Type-Specific Variants across 11 Common Diseases.
A Gusev, SH Lee, G Trynka, H Finucane, BJ Vilhjálmsson, H Xu, C
Zang, S Ripke, B Bulik-Sullivan, E Stahl, Schizophrenia Working Group of
the Psychiatric Genomics Consortium, SWE-SCZ Consortium, AK Kahler, CM
Hultman, SM Purcell, SA McCarroll, M Daly, B Pasaniuc, PF Sullivan, B
Neale, NR Wray, S Raychaudhuri, AL Price.
https://doi.org/10.1016/j.ajhg.2014.10.004
Genome-wide association study of Arabidopsis thaliana leaf
microbial community.
MW Horton, N Bodenhausen, K Beilsmith, D Meng, BD Muegge, S
Subramanian, MM Vetter, BJ Vilhjálmsson, M Nordborg, JI Gordon, J
Bergelson.
http://dx.doi.org/10.1038/ncomms6320
Effect of genetic variation in a Drosophila model of
diabetes-associated misfolded human proinsulin.
BZ He, MZ Ludwig, DA Dickerson, L Barse, B Arun, BJ Vilhjálmsson,
S-Y Park, NA Tamarina, SB Selleck, PJ Wittkopp, GI Bell, M
Kreitman.
https://doi.org/10.1534/genetics.113.157800
The nature of confounding in genome-wide association studies.
BJ Vilhjálmsson and M Nordborg.
https://doi.org/10.1038/nrg3382
Quantifying missing heritability at known GWAS loci.
A Gusev, G Bhatia, N Zaitlen, BJ Vilhjálmsson, D Diogo, EA Stahl, PK
Gregersen, JWorthington, L Klareskog, S Raychaudhuri, RM Plenge, B
Pasaniuc, AL Price.
https://doi.org/10.1371/journal.pgen.1003993
Massive genomic variation and strong selection in Arabidopsis
thaliana lines from Sweden.
Q Long, FA Rabanal, D Meng, CD Huber, A Farlow, A Platzer, Q Zhang,
BJ Vilhjálmsson, A Korte, V Nizhynska, V Voronin, Ü Seren, L Sedman, I
Hellmann, M Nordborg.
https://doi.org/10.1038/ng.2678
Genetic architecture of skin and eye color in an
African-European admixed population.
S Beleza, NA Johnson, SI Candille, DM Absher, MA Coram, J Lopes, J
Campos, II Araújo, TM Anderson, BJ Vilhjálmsson, M Nordborg, A Correia e
Silva, MD Shriver, J Rocha, GS Barsh, H Tang.
https://doi.org/10.1371/journal.pgen.1003372
JAWAMix5: an out-of-core HDF5-based java implementation of
whole-genome association studies using mixed models.
Q Long, Q Zhang, BJ Vilhjálmsson, Ü Seren, P Forai, M
Nordborg.
https://doi.org/10.1093/bioinformatics/btt122
Multilocus mixed model for genome-wide association studies in
structured populations.
V Segura, BJ Vilhjálmsson, A Platt, A Korte, Ü Seren, Q Long, and M
Nordborg.
https://doi.org/10.1038%2Fng.2314
A mixed model for genome-wide association studies of
correlated traits in structured populations.
A Korte, BJ Vilhjálmsson, V Segura, A Platt, Q Long, and M
Nordborg.
https://doi.org/10.1038/ng.2376
GWAPP: A web application for genome-wide association studies
in A. thaliana.
Ü Seren, BJ Vilhjálmsson, MW Horton, D Meng, P Forai, YS Huang, Q
Long, V Segura, and M Nordborg.
https://doi.org/10.1105/tpc.112.108068
Genome-wide patterns of genetic variation in worldwide
Arabidopsis thaliana accessions from the RegMap panel.
MW Horton, AM Hancock, YS Huang, C Toomajian, S Atwell, A Auton, NW
Muliyati, A Platt, FG Sperone, BJ Vilhjálmsson, M Nordborg, JO Borevitz,
J Bergelson.
https://doi.org/10.1038%2Fng.1042
Analysis and visualization of Arabidopsis thaliana GWAS using
web 2.0 technologies.
YS Huang, M Horton, BJ Vilhjálmsson, Ü Seren, D Meng, C Meyer, MA
Amer, JO Borevitz, J Bergelson, and M Nordborg.
https://doi.org/10.1093/database/bar014
Genome-wide association study of 107 phenotypes in
Arabidopsis thaliana inbred lines.
S Atwell, YS Huang, BJ Vilhjálmsson, G Willems, M Horton, Y Li, D
Meng, A Platt, AM Tarone, TT Hu, R Jiang, NW Muliyati, X Zhang, MA Amer,
I Baxter, B Brachi, J Chory, C Dean, M Debieu, J De Meaux, JR Ecker, N
Faure, JM Kniskern, JDG Jones, T Michael, A Nemri, F Roux, DE Salt, C
Tang, M Todesco, MB Traw, D Weigel, P Marjoram, JO Borevitz, J
Bergelson, M Nordborg.
https://doi.org/10.1038/nature08800
Conditions Under Which Genome-wide Association Studies Will
be Positively Misleading.
A Platt, BJ Vilhjálmsson, M Nordborg.
https://doi.org/10.1534/genetics.110.121665